Filiform papillae epithelium

The tapering filiform papillae seen here are the most numerous type, covering most of the anterior two thirds of the tongue. Each papilla is about two to three millimeters long and is composed of a conical tip of keratinized, stratified squamous epithelium and an underlying core of connective tissue. 100 Observations: The dome-shaped base of the human filiform papilla (primary papilla) is surmounted by 3 to 8 elongated structures (secondary papillae). These secondary papillae are composed of a central column of epithelial cells expressing hair-type keratins and an outer rim of cells expressing skin-type keratins (Papilla: small protuberance, Filum: thread) Filiform papillae are keratinous structures emerging from the surface of the tongue epithelium. They are densely packed on the central axis and more sparse on the lateral edges filiform papillae cover the dorsal tongue from the sulcus terminalis to the tip

Tongue: Filiform papillae - Tongue 2 Digital Histolog

Filiform papillae are the most common. They are keratinised and in the living, they look white. Fungiform papillae are not keratinised, but are highly vascularised. In the living, they look red. most of the fungiform papillae have some taste buds THE DORSAL surface of mammalian tongue is covered by densely packed filiform papillae. The shape and size of these papillae vary markedly from species to species. 1-8 In humans, the papillary architecture is more complex, consisting of a central body surrounded by several threadlike cornified projections, often referred to as secondary papillae. 5,9 Morphologically, human tongue epithelium.

Architectural organization of filiform papillae in normal

A fourth type of papilla, filiform papillae, are devoid of taste buds and are believed to be involved in texture perception, but the details of both the mechanical and molecular aspects of filiform papillae in encoding food texture are still unknown filiform papillae. Rough tongue surface. fungiform papillae. Mushroom-like protuberances often containing taste buds and located on the sides and tip of the tongue. Epithelium transitions into stratified squamous, external anal sphincter = skeletal muscle = voluntary control, internal anal sphincter = smooth muscle = involuntary. Science > Biology > Digestion and absorption in Human > Buccal cavity - Mouth The digestive system in humans consists of an alimentary canal and associated digestive glands. The human alimentary canal (aliment: nourish) is a continuous muscular digestive tube about 8 to 10 m long that runs through the body

Non keratinized stratified squamous epithelium b. Keratinized stratified squamous epithelium c. Simple squamous epithelium d. Pseudostratified squamous epithelium e. Both a and b. 4. Filiform papillae b. Circumvallate papillae c. Fungiform papillae d. Foliate papillae e. All of the above. 9. What is the innermost layer of the GI tract. Filiform tongue papillae as epithelial protrusions and epithelial ridge structures are thus clearly identified by his-tology and scanning electron microscope (SEM) analysis on new-born mice (Fig. 1C-E, data not shown). Although the anterior part of the Ikka mutant tongue often showed fusion of the entir The epithelium of the oral cavity and tongue forms a unique set of appendages (teeth, filiform papillae, taste papillae, and salivary glands) that are all functionally involved in food ingestion. The true tongue, defined as having voluntary muscles and being movable, is a vertebrate-specific organ The results showed that the filiform papillae were covered by a biestratified epithelium formed by a basal layer of dendritic cells and an upper surface layer consisting of numerous seromucous secretory cells, dendritic cells apical processes, and some goblet cell-like and ciliated cells Heavy keratinization of filiform papillae, occurring for instance in cats, gives the tongue a roughness that is characteristic of these animals. These papillae have a whitish tint, owing to the thickness and density of their epithelium

At P0, rudiments of filiform papillae showed a similar distribution to that seen in the adult, but had a more rounded appearance. The columnar structure of cells in the epithelium, with the different degrees of keratinisation as observed in the mature adult, was indistinct, but a keratinised layer was clearly located at the tip of each filiform. Filiform papillae with their conical morphology surround a fungiform papilla, which protrudes slightly above the filiform. Both types of papillae are covered by a keratinized epithelium. Although scattered taste buds may be present on the dorsum of fungiform papillae, none are visible here. 100 In young children, the fungiform papillae can be seen with the naked eye as red spots on the dorsum of the tongue (because the non-keratinized epithelium is relatively translucent). These papillae are less readily observed in adults, because of slight keratinization of the epithelium

Filiform Papillae SpringerLin

Fungiform and filiform papillae. Human, Zenker's fluid, phosphotungstic acid hematoxylin, 26 x. Fungiform papillae: Mushroom-like. Larger but much less frequent than filiform papillae. Has a stratified squamous non-cornified epithelial covering and a highly vascularized connective tissue core giving it a red hue in the living state 1.1. Filiform papilla:Filiform papilla: Makes up majority of the papillae and covers the anterior part of the tongue. They appear as slender, threadlike keratinized projections (~ 2 to 3 mm) of the surface epithelial cells. These papillae facilitate mastication (by compressing and breaking food when tongue is apposed to the hard palate) and.

OBSERVATIONS: The dome-shaped base of the human filiform papilla (primary papilla) is surmounted by 3 to 8 elongated structures (secondary papillae). These secondary papillae are composed of a central column of epithelial cells expressing hair-type keratins and an outer rim of cells expressing skin-type keratins They contain an ortho-keratinized or para-keratinized stratified squamous epithelium ← over a highly vascular sub-mucosa, giving these structures a more reddish-appearance than neighboring filiform papillae. The epithelial layer contains taste buds, which detect the sense of gustation, which is in turn a part of the perception of taste The results demonstrated that there are thick polygonal keratinized epithelial cells where groups of bacteria are revealed in three-dimensional images on the surface of filiform papillae in these animals. The bacterial membranes are randomly attached to the microplicae surface of epithelial cells Filiform papillae. Filiform papillae is covered on the dorsal surface of the mammals . tongue. Histological, each filiform papillae consist of essentially two parts: a stratified squamous epithelium, including a basal cell layer and a cornified, curved spine projecting from the surface. Each of the filiform papillae has a connective tissue core A) Conical filiform papillae formed of columnar epithelium containing tubular gland. Although, it was related that the filiform papillae of tongue presented morphological variations not only between the species, but also between different localizations on the tongue surface

1. area of nonkeratinized epithelium surrounding each papilla. 2. minor salivary gland. 3. mechanical function= pointed to postior. fungiform papillae. 1.CT core: lamina propria 2. tied down to muscle. fewer taste buds than circumvallate (2-5) 3. taste buds on teh dorsal side of papilla Both tongue papillae and epidermis are stratified epithelial structures. Filiform papillae at the MVE-AE region were observed as a thin epithelial layer in Ikkα mutants, whereas Ikkα mutant epidermis is markedly thicker (Hu et al., 1999). The function of Ikkα in epithelium is thus different between skin and filiform papillae

Oral: The Histology Guid

Fungiform papillae contain an ortho-keratinized or para-keratinized epithelial layer over a highly vascular sub-mucosa, giving these structures a more reddish-appearance than neighboring filiform papillae. The epithelial layer contains taste buds, which detect the sense of gustation, which is in turn a part of the perception of taste Oral tongue mucosa: modified keratinized squamous epithelium with small papillae; papillae can be filiform (majority, conical projections of keratinized epithelium), fungiform (rounded elevations, nonkeratinized), foliate (along sides of tongue) or cirucumvallate (at junction of anterior 2/3 and posterior 1/3 tongue, largest papillae The papillae on the tongue are located anteriorly to the sulcus terminalis. The tongue contains primarily three types of papillae: filiform papillae, circumvallate papillae and fungiform papillae. The filiform papillae are the smallest and most abundant. Filiform papillae are the only papillae on the tongue which do not contain taste buds Section Through a Filiform Papilla. Note the layer of keratin (A) at the tip of this filiform papilla (B). There is non-keratinized stratified squamous epithelium on either side of the tip. The papillae has a core of loose connective tissue, or lamina propria (C). The tongues of animals that feel much rougher (such as the cat) reflects the. Texture perception of foods is a common yet remarkably unstudied biophysical problem. Motivated by recent experiments reporting the presence of corpuscular endings in tongue filiform papillae, we develop in this work a mechanical model of the human tongue covered with filiform papillae in the form of elastic beams. Considering the typical flows that occur in the mouth during oral evaluation of.

Architectural Organization of Filiform Papillae in Normal

The filiform papillae is numerous types and slender, threadlike structure that project above the surface of the tongue. Filiform pappilae of animal tongue lines with keratinized stratified squamous epithelium with a thick stratum corneum. Taste buds are the ellipsoid cluster of specialized epithelial cells that founds in the surface. Filiform Papillae Further Characteristics •Epithelial cells contain keratin-bundling proteins •Filaggrins •Co-localize with trichohyalin protein •Crucial in the keratinization process •Nerve supply •Three types of nerve endings •Free unmyelinated-extend to subepithelial C The molecular mechanisms of filiform tongue papillae development however are not fully understood.We found Ikkα and Irf6 expression in developing tongue epithelium, and describe here specific tongue abnormalities in mice with mutation of these genes, indicating a role for Ikkα and Irf6 in filiform papillae development On some of the filiform papillae the epithelial prolongations stand erect, in one they are spread out, and in three they are folded in. The filiform papillae (singular: papilla) are one of the four types of lingual papillae, small prominences on the surface of the tongue. The filiform papillae are thin, long V-shaped cones that don't contain.

Sensing in the Mouth: A Model for Filiform Papillae as

  1. a propria Striated muscle Fig. 4q.—Tongue with papillae and taste bud. (X400.) present in much smaller
  2. Filiform papillae. Filiform papillae is covered on the dorsal surface of the mammals . tongue. Histological, each filiform papillae consist of essentially two parts: a stratified squamous epithelium, including a basal cell layer and a cornified, curved spine projecting from the surface. Each of the filiform papillae has a connective tissue core
  3. The filiform papillae were curved, enclosed a large connective tissue core and were separated by wide inter‐papillary zones covered by a thick epithelium. Most filiform papillae had a cylindrical shape, but the rostral and central parts of the tongue contained a number of flat, comb‐shaped papillae with rounded tips
  4. Introduction The epithelium of the oral cavity and tongue forms a unique set of appendages (teeth, filiform papillae, taste Ectodermal appendages, including scales, teeth, feathers, papillae, and salivary glands) that are all functionally hair, nails, and a variety of eccrine glands such as mammary, involved in food ingestion
  5. sent loss of filif0rm papillae and a thinning of the epithelium. The white border is composed of regenerat-ing filiform papillae and a mixture of keratin and neu-trophils. The surface is nonulcerated, but appears ulcer-ated due to the loss of the surface papillae and keratin

Anatomy Unit 3 Digestive and Respiratory System Flashcards

filiform papillae - tongue smallest and most numerous papillae, provide a rough surface to aid in the manipulation and processing of foods. fungiform - L. fungus = mushroom + forma = a shape; of lingual papillae. fungiform papillae - tongue single evenly spaced between the filiform papillae. Epithelium is slightly thinner than on the remaining. The lingual papillae are vertical elevations or projections of the epithelial surface, and they contain a core of connective tissue derived from the lamina propria. In this section there are a number of filiform papillae and a single circumvallate papilla. Note the numerous taste buds on the lateral walls of the circumvallate papilla filiform papillae: [TA] numerous elongated conic keratinized projections on the dorsum of the tongue. Synonym(s): papillae filiformes [TA A pronounced species variation in the organization of filiform papillae has been observed. Preliminary histologic studies of cat tongue revealed marked regional variations in size, shape and organization of filiform papillae. Therefore, a correlated light microscopic, transmission and scanning electron microscopic study of tissue samples of representative areas of the cat tongue was undertaken. filiform papillae consist of essentially two parts: a stratified squamous epithelium, including a basal cell layer and a cornified, curved spine projecting from the surface. Each of the filiform

Filiform Papillae Archives - The Fact Facto

(e) The fungiform papillae (arrow) exhibited dome-like shape between conical filiform papillae and the highlighted taste orifice (arrowhead) may be seen in the surface. (f) After the removal of the epithelium, the CTCs of the fungiform papillae revealed volcano-like shape, with a cavity on the top for the taste buds (arrow) ing. During embryonic period, the filiform papillae and hair-like papillae are not formed. The embryonic epithelium that covered the mechanical papillae undergoes transformation leading to the formation of multilayered epithelium. During prehatching stage, epithelium becomes orthokeratinized epi-thelium.Inconclusion,the tongueofthedomesticgoose. Filiform papillae - have an elongated conical shape. * These papillae are numerous and are found over the entire dorsal surface. * There are no taste buds in the epithelium covering filiform papillae. * The filiform papillae are covered by a keratinized stratified squamous epithelium. b. Fungiform papillae - these are mushroom shaped

Histology-World! Histology Testbank-Gastrointestinal System

  1. ation may reveal an acute and chronic inflammatory infiltrate in the submucosa with epithelial edema. It is associated with neutrophils for
  2. alis lies a V-shaped line of circumvallate papillae, and on the posterior aspects of the lateral margins of the tongue lie the foliate papillae. This epithelium has undergone a peculiar.
  3. Anatomy A215 Virtual Microscopy. The tongue lies on the floor of the mouth. It is composed of interlacing bundles of skeletal muscle and is covered by stratified squamous epithelium. The surface of the anterior two-thirds of the tongue contains numerous small projections called papillae
  4. Any of the large papillae near the base on the dorsal aspect of the tongue, arranged in a V-shape. The taste buds are located in the epithelium of the trench surrounding the papilla
  5. Filiform papillae, which are the most numerous and appear short and bristled. Their surface is keratinized. Fungiform papillae, which are scattered among the filiform papillae and are larger, redder, and more globular. They are not keratinized. Circumvallate papillae, which contain the most taste buds. There are between 6 and 14 circumvallate.
  6. Synonyms for Filiform papillae in Free Thesaurus. Antonyms for Filiform papillae. 14 words related to papilla: appendage, outgrowth, process, phytology, botany, sense.
  7. Filiform papillae - Papillae filiformes owing to the thickness and density of the epithelium of which they are composed, which has here undergone a peculiar modification, the cells having become cornified and elongated into dense, imbricated, brush-like processes. They contain also a number of elastic fibers, which render them firmer and.

Regional Regulation of Filiform Tongue Papillae

the type and in the distribution of filiform papillae remains to be resolved in the future. Farbman (1970) was the first to report that the dorsal epithelium of the rat tongue consists of three identifiable types of epithelium, that on the anterior side of the filiform papillae, the epithelium on the posterior side of the filiform Tongue epithelium is a morphologically variable tissue with diverse structures. K36 immunostaining was localised solely to filiform papillae and not detected in other structures . Within the filiform papilla, K36 was present in the cytoplasm of epithelial cells organised in arcs at the periphery

Pax9 is required for filiform papilla development and

  1. Manabe M, Lim HW, Winzer M, Loomis CA. Architectural organization of filiform papillae in normal and black hairy tongue epithelium: dissection of differentiation pathways in a complex human epithelium according to their patterns of keratin expression. Arch Dermatol. 1999 Feb;135(2):177-81. PubMe
  2. There are four types of lingual papillae found on the surface of the human tongue. These include: Filiform papillae are the most abundant of the four types of papillae. They are stretched, conical, grey-white papillae that are covered in a heavy coat of keratinized squamous epithelium
  3. The surface of the epithelium bears a series of ridges (arrow) that represent the bases of conical projections called Filiform Papillae. The filiform papillae, which do not contain taste buds, give a rough texture to the surface of the tongue that provides traction against material to be moved in the mouth

[New observations on the structure of the lingual filiform

  1. a propria . and submucosa. large filiform papillae . that are heavily keratinized . fungiform papillae . with taste buds . unilocular adipose tissue present . that is common for this species
  2. papillae filiform ដែលត្រូវបានគេហៅថា papillae.
  3. a Propria interdigitates. Connective Tissue Ridges or Papillae: upward projections of LP o Dermal papillae in skin. Rete Ridges: pegs, downward projectio
  4. ently observed on the lingual papillae on the dorsal surface of the tongue (Fig. 1). Biopsy showed taper-ed finger-like projections covered with keratinized strati-fied squamous epithelium, suggesting the involvement of filiform rather than fungiform papillae. Acanthosis, papil-lomatosis, and parakeratosis with sparse lymphocytic infl
  5. Taste buds contain the taste receptor cells, which are also known as gustatory cells. The taste receptors are located around the small structures known as papillae found on the upper surface of the tongue, soft palate, upper esophagus, the cheek, and epiglottis.These structures are involved in detecting the five elements of taste perception: saltiness, sourness, bitterness, sweetness and umami
  6. a propria covered by stratified squamous keratinized epithelium. Fungiform papaillae- present mainly at the tip and sides of dorsal surface, mushroom shape with core of la

Filiform Papillae. The filiform papillae are the most numerous types, forming a velvety covering on the tongue. Their shapes vary among different animal species. Equine filiform papillae appear as thin cornified threads projecting above the surface and their connective tissue cores end at the bases of the cornified threads The filiform papillae are thin, long papillae V-shaped cones that don't contain taste buds but are the most numerous. These papillae are mechanical and not involved in gustation covering most of the dorsal (top). Characterized increased keratinization. papillae (projections) . They are small and arranged in lines parallel to the V-shaped row of circumvallate papillae, except at the tip of.

The filiform papilla in this portion is a circular conical type. It is composed of a base (Ba) and processes. The external shape of the Ba is elliptical columnar, and a main process (M) is inclined in the direction of the pharynx. There are ten accessory processes. Vol. 49, No. 1 Epithelial papillae and microvascular architecture of cat. The filiform papillae are anatomically placed directly above the dermal papillae-the latter are seen in sections as prominent indentations of dermis into the basal surface of the squamous epithelium, separated by the rete ridges When the epithelium is stripped from the dermis, and viewed with a scanning electron microscope, the basal surface is. Atrophic glossitis is a condition characterized by the absence of filiform or fungiform papillae on the dorsal surface of the tongue. Consequently, the ordinary texture and appearance of the dorsal tongue, determined by the papillary protrusion, becomes a smooth-looking epithelium HA5 shows a filiform papilla. This image is perpendicular to HA2. You can see the layers of the stratified squamous keratinizing epithelium in this image. Filiform papillae do not have taste buds. They have a sensory function. Note the nerve bundles near the center (arrows). The epithelium on the dorsal surface of the tongue is keratinized, but. Presents on the dorsal surface of the tongue when normal shedding of the epithelium of the filiform lingual papillae does not occur. As a result, a thick layer of dead cells and keratin builds up on the surface of the tongue, which then becomes extrinsically stained by tobacco, medicines, or colored oral bacteria

Section of a Fungiform Papilla. In the center of the field is a fungiform papilla (A). To either side are filiform papillae (B). Fungiform papillae are roughly mushroom-shaped. Their apical surface is not initially keratinized. The capillaries in the connective tissue core (C) show through the more translucent surface. This gives them their. Arrow indicates the basal epithelial layer. (b) Whole mount immunofluorescent staining for E-cadherin and DAPI of the isolated tongue epithelium. Arrows indicate important structures in the epithelium. Abbreviations: bl, basal layer; epi, epithelium; fp, filiform papillae; mes, mesenchyme; tb, taste bud. Scale bars: Ba, Ca: 100 μm; Bb, Cb: 30 μm Filiform papillae are the most numerous and are conical in structure consisting of a surface covering of stratified squamous keratinized epithelium with a lamina propria core . They are found in parallel rows across tongue and function for licking (rough tongue) and contain nerve endings for touch ( Filiform 2 )

Lingual papillae - Wikipedi

  1. The epithelium of the dorsal surface is thrown up into papillae; the ventral surface is smooth and the epithelium is thinner. Note the arrangement of the muscle of the tongue and the distribution of blood vessels and nerves within it. Identify the numerous filiform papillae on the dorsum of the tongue
  2. Figure 8 shows filiform papillae. Filiform papillae are pointed structures which are directed caudally; they have a core of connective tissue lined by keratinized stratified squamous epithelium. taste buds taste buds fungiform fungiform papilla papilla filiform filiform papilla papilla 7 7 8
  3. filiform papillae, which appear as slender, stalked projections coveredat their tips bya denselayer of microorganisms. The compact epithelial cells deep to the papillae show a scattering of keratohyalin (eleidin) granules. Anarrowstrip ofthesubmucosal connectivetissueis includedinnearlyallthebiopsies, but no muscle fibres or salivary tissue.

Filiform-like Fungiform Papillae—Fungiform papillae occasionally undergo major structural transformation following denervation of the CT and/or lingual nerve. They can develop a conical protrusion on the epithelial surface that has been described as filiform-like because of the resemblance to filiform papillae Vallate Papillae - Trip Database. How to Trip Rapid Review. Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies) Step 2: press. Analyse Reviews. Step 3: review the result, and maybe amend the sentiment or sample size if you know better

Science Source - Lingual Papilla and Taste Buds, Illustration

• The reason for this is that some areas of tongue have normal epithelium while at some areas these is inflamed epithelium. 16. HISTOLOGICAL FEATURES • Thinning Of Epithelium At Center Of Lesion • HYPERPLASIA & HYPERKERATOSIS AT PERIPHERY • Chronic inflammatory cells in underlying connective tissue • Loss Of Filiform Papillae At The. The Papillae. 1. The mucosa has numerous minute lingual papillae: • (1) the filiform papillae, the narrowest and most numerous; Filiform Papillae • = plush of tongue • Parallel rows • Primary columnar elevation of lamina propria • 5 - 30 tall secondary papillae • Epithelium over papillae - end in tapered points • Hard & scaly (no The anterior tongue comprises both taste epithelium, i.e. distributed fungiform taste papillae housing individual taste buds, as well as the predominant non-taste epithelium occupied by mechanosensory filiform papillae (Fig. 1A-A″) (Nosrat et al., 2000). Adult mice carrying KRT14-cre/ERT2 (Li et al., 2000 Tongue, papillae with taste buds (foliate papillae from rabbit). Notes. Fungiform papilla appear as occasional small pink projections which are scattered rather widely over the surface of the human tongue. Taste buds on the human tongue are found ONLY on the sides of fungiform papillae (and on a few large circumvallate papillae located at the back of the tongue) The epithelium of the dorsal surface of the tongue has three types of papillae: fungiform, filiform, and circumvallate (vallate). The tongue is innervated by four cranial nerves, the fifth or trigeminal, the seventh or facial, the ninth or glossopharyngeal, and the twelfth or hypoglossal

D. Absence of filiform papillae # Burning sensation of tongue is called: A. Glossopyrosis B. Glossodynia C. Glossitis D. Glossolgia # A median round lesion in front of circumvallate papillae, with epithelial hyperplasia diagnosis is: A. Median rhomboid glossitis B. Erythema migrans C. Aphthous ulcer D. Chemical bur Taste buds are found primarily in the tongue papillae. The tongue contains 4 types of papillae, the most common type, filiform, are thin and wire shaped and do not contain taste buds. On the dorsal, anterior border of the tongue are mushroom shaped papillae, fungiform,these have taste buds located near the middle or in a cleft of the papillae In mammals, the adult lingual epithelium can be categorized into non-taste and taste components. The majority of the tongue surface is covered by keratinized, non-taste epithelium made up of mechanosensory filiform papillae, which are curved, spinous-shaped structures with small mesenchymal cores (Hume and Potten, 1976).The more complex taste epithelium consists of collections of.


Ultrastructural study of the relationship between the

olfactory epithelium respiratory epithelium trachea vocalis m. This section was taken from the anterior dorsal part of the tongue which is rich in filiform papillae. Foliate papillea are found in in infant humans, but not in adults. Many other mammals have a lot of foliate papillae in adults as well as infants The vallate papillae had also different shapes. Taste buds were demonstrated within the epithelium of the dorsal surfaces of the fungiform papillae and the lateral surfaces of the vallate papillae. In addition, a longitudinal row of large papillae was located on the lateral aspect of the tongue in relation to the filiform papillae fungiform, circumvallate, foliate and filiform papillae. With the exception of the filiform papillae, these types of papillae contain taste buds and are known as the gustatory papillae. The gustatory papillae and the other epithelial appendages, including the teeth, feathers and hair. This is because 1 papillae and taste pores were easily differentiated from filiform papillae under darkfield and phase-contrast microscopy. Fungiform Papillae with Pores—Fungiform papillae appeared as circular eminences on the surface of the epithelium (Miller and Reedy, 1990). Taste pores appeared as small Foliate papilla with sensory taste bud structures located on the sides of the papilla F: fungiform papilla FI: filiform papillae composed mostly of keratinized epithelium V: vallate papilla TB: taste buds DENTITION | THE TEETH 32 adult teeth; 20 deciduous (primary or baby) teeth ° Adult dental pattern • 2 arches of teeth in maxillary and.

BGDB Practical - Upper Gastrointestinal Tract HistologyHistology - Oral Cavity and Esophagus at University of79: Oral Mucosa and Mucosal Sensation | Pocket DentistryTypes of papillae on tongue | Intelligent DentalFlashcards - GI Histology - epithelium of the oral mucosa

that epithelial appendages utilize discrete mechanisms for morphogenesis, with LGN being required for the proper development of filiform papillae but dispensable for hair follicle growth. RESULTS Oral epithelial development is diverse and dynamic To investigate how OE development comparesto that of epidermis circumvalate papilla crown, anatomical and clinical dental lamina dental papillae dentin dentinal tubules enamel filiform papilla fungiform papilla gingiva inner enamel epithelium intercalated duct interlobular duct lingual tonsil lip minor salivary glands odontoblast oral mucosa outer enamel epithelium parotid gland periodontal ligamen fungiform papillae: [TA] numerous minute elevations on the dorsum of the tongue, the tip being broader than the base and resembling a mushroom; the epithelia of many of these papillae contains taste buds. Synonym(s): papillae fungiformes [TA], clavate papillae To test whether HPI altered turnover in lingual epithelium, we studied cell proliferation within FP and the nontaste filiform papillae. In FP we designated three regions, basal, apical, and perigemmal zones of FP basal cells ( Fig. 2 A , vehicle), and quantified Ki67 + cells for proliferation